
ANSES reaffirms the need to limit oral exposure to nano titanium dioxide
The French National Agency for Health Safety (Anses) has published today a risk assessment called “nano specific” of titanium dioxide used as a food additive (E171). This is the third part of the process initiated by ANSES in 2020 regarding nanomaterials in food products and the first application of the risk assessment methodology specific to nanomaterials used as food additives established by ANSES in 2021.
In this assessment, the agency reports the lack of toxicological data available to perform a complete evaluation of the additive E171. This is unfortunate because it prevented the agency from completing the risk assessment of the additive E171. “The experts have identified all the data that will have to be produced on this nanomaterial: they concern general toxicity, genotoxicity, carcinogenicity, neurotoxicity or reproductive and developmental toxicity” explains Bruno Teste, coordinator of the assessment and scientific project manager in the food risk assessment unit of the Anses.
The Anses concludes by reaffirming its recommendation to limit the use and exposure of workers and consumers to nanomaterials, “by promoting the use of safe products, free of manufactured nanomaterials, and by limiting these uses to those considered in fine as duly justified and subject to a documented demonstration of risk acceptability”.
These conclusions raise some questions: despite the ban on the additive E171 in food which came into force in France in January 2020 and in Europe in August 2022, titanium dioxide nanoparticles are still authorized and used in many everyday products including in cosmetic products, hygiene products or medicines.

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Upcoming Nano Agenda

- Citizen webinar for the general public and the university community.
- Organizers: Research department Law & Social transformation (DETS), University of Bordeaux
- Speakers:
- Marion Tissier-Raffin, Senior Lecturer in Public Law, Centre de recherche et de documentation européennes et internationales (CRDEI), University of Bordeaux
- Mathilde Detcheverry, General Delegate, Association AVICENN – Veillenanos
- Didier Morin, University Professor of Neuroscience, UMR CNRS INCIA, University of Bordeaux
- Website: https://dets.u-bordeaux.fr/animation-scientifique/webinaires-citoyens/saison-2024-2025

- 5th Joint Symposium on Nanotechnology
- Organizers: the Fraunhofer Nanotechnology Network, with the support of the Federal Institute for Risk Assessment (BfR)
- Date: May 13-14, 2025
- Topics:
- the application of nanotechnology in various sectors, including digitalization, 2D/3D printing, carbon-based materials and battery materials
- nano on various regulations (REACh, food contact materials, cosmetics, bioagents, PPPs)
- adaptation and development of OECD Test Guidelines for nano and advanced materials (Malta Initiative)
- review on nano-specific NAMs (new approach methodologies)
- when you’re nano and you know it: dealing with uncertainty regarding the nanomaterial definition in regulatory frameworks
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- Website: www.isc.fraunhofer.de/…2025/5th-symposium-nanotechnology.html
- 4-day training :
- the different routes by which toxic substances can enter the body
- the importance of toxicokinetics in preventing the toxicity of substances,
- the absorption, distribution, metabolisation and elimination of xenobiotics
- the toxicity of nanoparticles
- Organizer : Association Toxicologie Chimie (ATC)
- From May, 19 to May, 22
- Speakers :
- Frédéric Gaidou (Chemical engineer specialising in Toxicology, ERAMET Group, Paris, President ATC Paris)
- Sarah Dognin dit Cruissat (Doctor of Pharmacy, nutritionist, toxicochemist, CALMEVA, Lyon)
- Jean-Dominique Puyt (Veterinary Doctor, Honorary Professor at the École Vétérinaire, Nantes)
- Isabelle Malissin (Doctor, Hôpital Lariboisière, Paris)
- Nicole Proust (Research Engineer, Honorary Director of Research at the CNRS, Specialist in Nanotechnologies, Arsenic, Electromagnetic Waves, Palaiseau)
- Marie-Chantal Canivenc-Lavier ((Nutri-toxicologist, Centre des Sciences du Goût et de l’Alimentation INRA-Dijon)
- Claude Lesné (Doctor, Honorary Senior Research Engineer at the CNRS)
- Nicole Proust (Ingénieure Recherche, Directeur de recherche honoraire du CNRS, Spécialiste Nanotechnologies, Arsenic, Ondes électromagnétiques, Palaiseau)
- Website : https://www.atctoxicologie.fr/notre-formation.html